Table 5 - Novel technique for microbial production of 3,4-Dihydroxy Phenyl L-alanine by a mutant strain of Aspergillus oryzae

Table 5. Comparative study of L-DOPA production and kinetic parameters (specific rate constants) by both parental (GCB-6) and mutant (UV-7) strains of Aspergillus niger.

Incubation period (Hours)	Specific rate constants (mg/mg/h)
	q_p		q_s
	Parent	Mutant	Parent	Mutant
24 36 48 60 72 84 96	0.00184±0.0001 0.00321±0.0002 0.00270±0.0001 0.00170±0.0001 0.00117±0.00005 0.00068±0.00002 0.00335±0.0001	0.00107±0.0005 0.01283±0.003 0.03740±0.002 0.02646±0.002 0.01742±0.0005 0.01338±0.002 0.00881±0.0005	0.00420±0.0001 0.00585±0.0002 0.00645±0.0002 0.00586±0.0004 0.00560±0.0002 0.00509±0.0005 0.00364±0.0003	0.00173±0.0002 0.00905±0.0001 0.02065±0.005 0.01680±0.005 0.01334±0.002 0.01212±0.003 0.01322±0.0001

q_p = specific citric acid production rate (mg/mg/h) = (µ x Y_p/s); q_s = specific substrate uptake rate (mg/mg/h) = (µ x Y_x/s). The values differ significantly at p<0.0025 while ± indicates the standard deviation among the replicates.