**Figure 3. Currents through mSlo
and mSlo-GFP channels from transfected COS-7 cell membranes reconstituted
into lipid bilyers.**

**A**: The current-voltage
relationship of *mSlo *channels, with the solid line representing a linear
fit of 8 single channel experiments (n=5 for each data point). The standard
error of the mean (SEM) is less than the width of the points and the average
channel conductance was 265 pS. **B**: Voltage dependence of a typical single
*mSlo* channel. The solid line represents a least squares fit of the Boltzman
distribution. **C**: Single channel current (*mSlo*) activation by free
Calcium added to the internal side of the channel in 150 mM symmetrical KCl.
The data was least-squares fitted with the Hill equation (*K _{D}*
= 13.9 m M, n = 2.9, V

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