Electronic Journal of Biotechnology ISSN: 0717-3458
  © 2004 by Universidad Católica de Valparaíso -- Chile
Vol. 7 No. 3, Issue of December 15, 2004


Figure 3. Model for TGS with a central role for dsRNA. TGS is induced when the dsRNA consists of promoter sequences. DsRNAs are cleaved into small RNAs of 21-23 nt, and either these small RNAs or the dsRNA itself direct the methylation of corresponding DNA sequences. This promoter methylation inhibits transcription, as indicated by cross sign.

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