Electronic Journal of Biotechnology ISSN: 0717-3458
  © 2001 by Universidad Católica de Valparaíso -- Chile
Vol. 4 No. 1, Issue of April 15, 2001
 


Table 6. Effects on the A. niger idiophase synthesis and excretion citrate rates to changes in different metabolic processes.

Process

Perturbation
Magnitude
(%)

Expected Response (a) (%)

Citrate
Synthesis

Direct Citrate
Excretion

Net
Effect

Carbon
Availability

ATP
Availability

Glucose uptake (R1)

+100

+140

+ 280

-93

+ 47

Glycerol-P

Phosphatase (R11)

-100

+5.4

Null

-3.6

+1.8

R5P Reductase (R4)

-100

+1.9

Null

-1.3

+0.6

G6P-DH (R2)

-100

+12

Null

Null

R8

-100

-83

Null

+ 78

R16

+100

Null

+700

Null

ATP/ADP Carrier (R21)

-10

Null

+29

Cytoplasmatic

H+-ATPase (R19)

-10

Null

+155

-34

Mitochondrial

H+-ATPase (R20)

-10

Null

+116

+45

Pi Carrier (R22)

+100

Null

+333


(a) Calculated as (D Roptimized/Roptimized) 100 [dLn(Roptimized)/ dLn(Rperturbated)].(D Rperturbated/Rperturbated)100

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