Electronic Journal of Biotechnology ISSN: 0717-3458
  © 2008 by Universidad Católica de Valparaíso -- Chile
Vol. 11 No. 1, Issue of January 15, 2008
 


Table 1. Extent of conversion of Candida rugosa lipase-catalyzed esterification of ibuprofen at 48 hrs under various conditions.


Ibuprofen Concentration

60 mM

48 mM

36 mM

24 mM

 Isooctane

aw = 0.73

0.29 ± 0.01

0.23 ± 0.01

0.29 ± 0.01

0.27 ± 0.02

aw = 0.59

0.20 ± 0.01

0.21 ± 0.01

0.23 ± 0.01

0.24 ± 0.01

aw = 0.43

0.06 ± 0.01

0.06 ± 0.01

0.03 ± 0.02

0.03 ± 0.01

 2,5-Dimethylhexane

aw = 0.73

0.17 ± 0.04

0.12 ± 0.01

0.07 ± 0.01

ND

aw = 0.59

0.11 ± 0.01

0.09 ± 0.01

0.07 ± 0.01

ND

aw = 0.43

NR

NR

NR

ND

 2-Methylheptane

aw = 0.73

0.28 ± 0.01

0.25 ± 0.01

0.24 ± 0.01

0.24 ± 0.01

aw = 0.59

0.24 ± 0.01

0.21 ± 0.01

0.18 ± 0.01

0.23 ± 0.01

aw = 0.43

0.13 ± 0.002

0.056 ± 0.002

0.028 ± 0.002

NR

 n-Octane

aw = 0.73

0.26 ± 0.01

0.22 ± 0.05

0.21 ± 0.01

0.22 ± 0.01

aw = 0.59

0.24 ± 0.01

0.17 ± 0.01

0.18 ± 0.01

0.25 ± 0.01

aw = 0.43

0.074 ± 0.005

0.066 ± 0.008

0.086 ± 0.015

0.189 ± 0.001

ND: indicates the reaction was not performed.
NR: indicates no reaction was observed.


Supported by UNESCO / MIRCEN network