Electronic Journal of Biotechnology ISSN: 0717-3458
  © 2007 by Universidad Católica de Valparaíso -- Chile
Vol. 10 No. 2, Issue of April 15, 2007
 

Table 1. Pharmacokinetics of non-glycosylated and glycosylated rhGM-CSF in mice after a single ip injection.


  

Cmax
(nmol/mL)

tmax
(min)

t1/2 α
(min)

t1/2 β
(min)

CL
(mL/min)

non-glycosylated rhGM-CSF

0.018 0.001

20

10 2

260 80

0.26 0.07

glycosylated rhGM-CSF

0.0028 0.0005

30

60 10

1,500 200

0.09 0.02


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